Ethylene Oxide: Acute Four-Hour and One-Hour Inhalation Toxicity Testing in Rats

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Ethylene Oxide: Acute Four-Hour and One-Hour Inhalation Toxicity Testing in Rats

Ethylene oxide was tested on groups of rats for either 4-hour or 1-hour inhalation exposure, followed by 14 days of observation. Groups of five Sprague-Dawley rats/sex were exposed, and clinical signs and mortality were recorded. Clinical signs noted included irregular breathing, absence of certain reflexes, and tremors. Rats that died had moderate to severe pulmonary congestion. The calculated...

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ژورنال

عنوان ژورنال: Journal of Toxicology

سال: 2011

ISSN: 1687-8191,1687-8205

DOI: 10.1155/2011/910180